Tomoko Takano, MD, PhD
Primary Axis:
Endocrinology, Diabetes, Nutrition and Kidney Diseases
Email:
Email contact form Research Focus:
To delineate the mechanisms of glomerular epithelial cell injury that leads to proteinuria.Rho-GTPases, nephrology, proteinuria, glomerular epithelial cells, lipid mediators, eidosanoids, signal transduction, nephrin, src-family kinase
External Website:
External Website Keywords:
Rho-GTPases, nephrology, proteinuria, glomerular epithelial cells, lipid mediators, eidosanoids, signal transduction, nephrin, src-family kinase
Location:
Duff Medical Building Publications:
Zhu J, Sun N, Aoudjit L, Li H, Kawachi H, Lemay S, Takano T. Nephrin mediates actin reorganization via phosphoinositide 3-kinase in glomerular epithelial cells. Kidney Int 73: 556-566; 2008
Zhang H, Cybulsky AV, Aoudjit L, Zhu J, Li H, Lamarche-Vane N, Takano T. Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury. Am J Physiol-Renal Physiol 293: F148-F156; 2007.
Jones N, Eremina V, Blasutig IM, Ruston J, Bladt F, Li H, Larose L, Takano T, Quaggin SE, Pawson T. The Nck SH2/SH3 adaptor couples nephrin to actin reorganization and controls the functional architecture of kidney podocytes. Nature 440: 818-823; 2006.Liens connexesOnline version: Molecular and Cellular Biology
