Thomas P. S. Schricker, MD, PhD
Primary Axis:
Endocrinology, Diabetes, Nutrition and Kidney Diseases
Email:
Email contact form Research Focus:
Research objectives include: to study the mechanisms, by which body protein loss after surgery is mediated to evaluate anesthetic, nutritional and pharmacologic strategies to attenuate the catabolic response to major abdominal surgery; and to study glucose metabolism and insulin therapy in patients undergoing cardiac surgery.Surgical catabolism, regional anesthesia, glucose and protein metabolism, perioperative nutrition
Keywords:
Surgical catabolism, regional anesthesia, glucose and protein metabolism, perioperative nutrition, perioperative medicine and outcome
Location:
Royal Victoria Hospital Publications:
Sato T, Carvalho G, Sato H, Lattermann R, Matsukawa T, Schricker T: Glucose and insulin administration while maintaining normoglycemia during cardiac surgery using a computer assisted algorithm. Diabetes Technol Ther 13: 79-84; 2011
Carvalho G, Pelletier P, Albacker T, Lachapelle K, Joannis D, Hatzakorzian R, Lattermann R, Sato H, Marette A, Schricker T: Cardioprotective effects of glucose and insulin administration while maintainingnormoglycemia (GIN therapy) in patients undergoing coronary artery bypass grafting. J Clin Endocrinol Metab 96: 1469-147; 2011
Sato H, Carvalho G, Sato T, Lattermann R, Matsukawa T, Schricker T: The association of preoperative glycemic control, intraoperative insulin sensitivity and outcomes after cardiac surgery. J Clin Endocrinol Metab 95: 4338-4344; 2010
Sato H, Lattermann R, Carvalho G, Sato T, Metrakos P, Hassanain M, Matsukawa T, Schricker T: Perioperative glucose and insulin administration while maintaining normoglycemia (GIN therapy) in patients undergoing major liver resection. Anesth Analg 110: 1711-1718; 2010
Albacker TB, Carvalho G, Schricker T, Lachapelle K: High-dose insulin therapy attenuates systemic inflammatory response in coronary artery bypass grafting patients. Ann Thor Surg 86: 20-28; 2008
Schricker T, Meterissian S, Lattermann R, Adegoke O, Marliss EB, Mazza L, Eberhart L, Carli F, Nitschman E, Wykes L: Anticatabolic effects of avoiding preoperative fasting by intravenous hypocaloric nutrition: a randomized clinical trial. Ann Surg 248: 1051-1059; 2008
POISE Study Group: Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomized controlled trial. Lancet 371: 1839-1847; 2008
Schricker T, Gougeon R, Eberhart L, Wykes L, Mazza L, Carvalho G, Carli F: Type 2 diabetes mellitus and the catabolic response to surgery. Anesthesiology 102: 320-326; 2005
Schricker T, Meterissian S, Eberhardt L, Wykes L, Lattermann R, Carli F: Postoperative protein sparing with epidural analgesia and hypocaloric dextrose. Ann Surg 240: 916-921; 2004
Schricker T, Wykes L, Eberhart L, Lattermann R, Mazza L, Carli F: The anabolic effect of epidural blockade requires energy and substrate supply. Anesthesiology; 97: 943-951; 2002
