Stéphane Laporte, PhD

Our research focuses on determining the fundamental molecular and cellular mechanisms regulating G protein-coupled receptor (GPCR) responses. In particular, our laboratory uses cellular imaging approaches such as confocal microscopy to study in real time the dynamics of protein and signaling complexes involved in receptor desensitization, internalization and intracellular trafficking. These studies are pivotal to understand the molecular basis of hormonal receptor-related diseases such as hypertension, nephrogenic, diabetes insipidus, infection and cancer.Hormone and drug action, G protein-coupled receptors, receptor desensitization internalization and trafficking.