Riaz Farookhi, PhD
Primary Axis:
Human Reproduction and Development
Email:
Email contact form Research Focus:
Research is focused on the role of the wnt-signaling pathway and cadherin-mediated cell adhesion in ovarian follicular morphogenesis and patterning. The potential role of wnt-signaling deregulation and alterations in cadherin expression in ovarian tumorigenesis is an active area of investigation. Additional areas of study involve somatic-germ cell interactions in the ovary and the function of HOX cofactor genes in the oocyte and follicular cells.Ovary, follicle, granulosa cell, wnt, signaling, cell adhesion, patterning, gene regulation
Keywords:
Ovary, follicle, granulosa cell, wnt, signaling, cell adhesion, patterning, gene regulation
Location:
Royal Victoria Hospital Publications:
Villaescusa JC, Verrotti AC, Ferretti E, Farookhi R, Blasi F. Expression of HOX-cofactor genes during mouse ovarian follicular development and oocyte maturation. Gene 2004; 330: 1-7.
Machell NH, Farookhi R. E- and N-cadherin distribution during luteinization in the rat ovary. Reproduction 2003; 125: 791-800.
Ricken A, Lochhead P, Konogiannea M, Farookhi R. Wnt-Signaling in the Ovary: Identification and Compartmentalized Expression of wnt2, wnt2b, and frizzled-4 mRNAs. Endocrinology 2002; 143: 2741-2749.
