Peter Metrakos, MD

Primary Axis: 
Cancer
Secondary Axis: 
Infection and Immunity
Research Focus: 

Proteomic and genomic approach to study the ischemia/reperfusion injury during human liver translantation. The focus to date has been on the changes seen to the cytoskeleton.Proprotein convertase profiling in colorectal cancer liver metastases.Liver, transplantation, colorectal cancer liver metastases, proteomic, genomic, proprotein convertases

Keywords: 
Liver, transplantation, colorectal cancer liver metastases, proteomic, genomic, proprotein convertases
Location: 
Royal Victoria Hospital
Publications:
Emadali A, Muscatelli-Groux B, Delom F, Jenna S, Boismenu D, Sacks DB, Metrakos PP, Chevet E. Proteomic analysis of ischemia-reperfusion injury upon human liver transplantation reveals the protective role of IQGAP1. Mol Cell Proteomics 2006; 5:1300-1313.
Tzimas G, Chevet E, Jenna S, Nguyen DT, Khatib AM, Marcus V, Zhang Y, Chretien M, Seidah N, Metrakos P. Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases. BMC Cancer 2005; 17: 149.
Emadali A, Nguyen DT, Rochon C, Tzimas GN, Metrakos PP, Chevet E. Distinct endoplasmic reticulum stress responses are triggered during human liver transplantation. Journal of Pathology 2005; 207: 111-118