Patricia N. Tonin, PhD
Primary Axis:
Cancer
Secondary Axis:
Medical Genetics and Genomics
Email:
Email contact form Research Focus:
Research is focused on the identification and characterization of the genetic events associated with the development and progression of sporadic and hereditary ovarian cancer and the contribution of BRCA1 and BRCA2 in hereditary predisposition to breast and ovarian cancers in the French Canadian population of Quebec.Ovarian cancer, tumor suppressor genes, cancer susceptibility genes, gene expression microarray analyses, mutation analyses, genotyping and genomic analyses
External Website:
External Website Keywords:
Ovarian cancer, tumor suppressor genes, cancer susceptibility genes, gene expression microarray analyses, mutation analyses, genotyping and genomic analyses
Location:
Montreal General Hospital Publications:
Wojnarowicz PM, Breznan A, Arcand SL, Filali-Mouhim A, Provencher DM, Mes-Masson A-M, Tonin PN. 2008. Construction of a chromosome 17 transcriptome in serous ovarian cancer identifies differentially expressed genes. Int J Gynecol Cancer 18(5):963-75.
Arcand SL, Maugard CM, Ghadirian P, Robidoux A, Perret C, Zhang P, Fafard E, Mes-Masson AM, Foulkes WD, Provencher D, Narod SA, Tonin PN. 2008. Germline TP53 mutations in BRCA1 and BRCA2 mutation-negative French Canadian breast cancer families. Breast Cancer Res Treat. 108(3):399-408.
Cody, N, Ouellet V, Manderson EN, Quinn M, Filali-Mouhim A, Tellis, P, Provencher D, Mes-Masson A-M, Chevrette M, Tonin PN. 2007. Transfer of chromosome 3 fragments identified candidate regions involved in growth suppression of a human ovarian cancer cell line monoallelic for chromosome 3p. Oncogene 26(4):618-32.
