Nada Jabado, MD, PhD
Primary Axis:
Medical Genetics and Genomics Research Focus:
Research is in the field of pediatric brain tumours, more specifically in brain tumours from the astrocytic lineage. The main objective is to achieve a better characterization of molecular markers and pathways responsible for pediatric high grade astrocytoma formation in a large number of pediatric tumours.Results will provide insight into genetic pathways involved in the initiation and progression of pediatric high grade astrocytomas and will likely provide a rational framework for the development of efficient interventional therapies.
Keywords:
Paediatric high grade astrocytoma, genome and transcriptome analysis, protein analysis, laser capture microdissection
Location:
Montreal Children's Hospital Publications:
Faury D, Nantel A, Dunn SE, Guiot MC, Haque T, Hauser P, Garami M, Bognár L, Hanzély Z, Liberski PP, Lopez-Aguilar E, Valera ET, Tone LG, Carret AS, Del Maestro RF, Gleave M, Montes JL, Pietsch T, Albrecht S, Jabado N. Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors. J Clin Oncol 25(10):1196-208, 2007
Krishnamoorthy P, Alyaarubi S, Abish S, Gale M, Albuquerque P, Jabado N. Primary hyperparathyroidism mimicking vaso-occlusive crises in sickle cell disease. Pediatrics 118(2):e537-9, 2006
Tamra E. Werbowetski-Ogilvie, Nathalie Y.R. Agar, Roberta M. Waldkircher de Oliveira, Damien Faury, Jack P. Antel, N. Jabado and Rolando F. Del Maestro. Isolation of a natural inhibitor of human malignant glial cell invasion: inter alpha trypsin inhibitor heavy chain 2. Cancer Res 66:1464-72, 2006
