Mary M. Stevenson, MD, PhD
Primary Axis:
Infection and Immunity
Email:
Email contact form Research Focus:
The foci of research efforts in Dr. Stevenson's laboratory are 1) identification of host genes determining susceptibility to malaria; 2) investigation of the mechanism(s) of innate and adaptive immunity to blood-stage malaria; 3) malarial anemia; and 4) effect of co-infection with a gastrointestinal nematode on primary and vaccine-induced immunity to malaria. For her studies, she uses the mouse model of blood-stage Plasmodium chabaudi AS malaria.Malaria, Plasmodium, mouse models, cytokines, Th cell diversity, dendritic cells, genetics of host resistance
External Website:
External Website Keywords:
Malaria, Plasmodium, mouse models, cytokines, Th cell diversity, dendritic cells, genetics of host resistance
Location:
Montreal General Hospital Publications:
Min-Oo G, Fortin A, Stevenson MM, Gros P. Complex genetic control of malaria: positional cloning of the Char9 locus. J Exp Med 204: 511-524; 2007.Liens connexesOnline version: Journal of Experimental Medicine
Segura M, Su Z, Piccirillo C, Stevenson MM. Impairment of dendritic cell functions by excretory-secretory products: a potential mechanism for nematode immunosuppression. Eur J Immunol 37: 1887-1904; 2007.
Ing R, Segura M, Thawani N, Tam M, Stevenson MM. Interaction of mouse dendritic cells and malaria-parasitized erythrocytes: uptake, maturation and antigen presentation. J Immunol 176: 441-450; 2006.
