Kenneth Morgan, PhD

Research Focus: 

My research interests are human population genetics and genetic epidemiology with particular emphasis on pedigree analysis of complex traits in founder populations. Ongoing collaborations include the study of various traits in a North American population isolate, and segregation and linkage analysis of intermediate phenotypes contributing to calcium kidney stone formation in French Canadians. In the area of host resistance to infectious disease, my collaborations include identification of quantitative trait loci that contribute to bacterial and viral loads in mouse models.

Keywords: 
Human population genetics, genetic epidemiology, pedigree analysis
Location: 
Montreal General Hospital
Publications:
Brown, S.J., Y. Asai, H.J. Cordell, L.E. Campbell, Y. Zhao, H. Liao, K. Northstone, J. Henderson, R. Alizadehfar, M. Ben-Shoshan, K. Morgan, G. Roberts, L.J. Masthoff, S.G. Pasmans, P.C. van den Akker, C. Wijmenga, J.O. Hourihane, C.N. Palmer, G. Lack, A. Clarke, P.R. Hull, A.D. Irvine, and W.H. McLean: Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy. Journal of Allergy & Clinical Immunology 127:661-667; 2011
Murawski, I.J., R,W, Maina, D. Malo, L.M. Guay-Woodford, P. Gros, M. Fujiwara, K. Morgan, and I.R. Gupta. The C3H/HeJ inbred mouse is a model of vesico-ureteric reflux with a susceptibility locus on chromosome 12. Kidney International 78:269-278; 2010
Carroll S.F., J.C. Loredo Osti, L. Guillot, K. Morgan, and S.T. Qureshi. Sex differences in the genetic architecture of susceptibility to Cryptococcus neoformans pulmonary infection. Genes and Immunity 9:536-545; 2008
Loredo-Osti, J.C., N.M. Roslin, J. Tessier, T.M. Fujiwara, K. Morgan, and A. Bonnardeaux: Segregation of urine calcium excretion in families ascertained for nephrolithiasis: Evidence for a major gene. Kidney International 68:966-971; 2005