Jean I. Tchervenkov, MD

Primary Axis: 
Infection and Immunity
Research Focus: 

Main research activities include the role of donor specific transfusion in tolerance induction in vascularized solid organ transplantation; donor cell trafficking following donor-specific transfusion and the role of the thymus in allograft tolerance; and the effect of intraportal vein donor-specific transfusion on small bowel and other vascularized allograft survival. Other interests include that of the role of T&B cells in Allo & Xeno rejection.Clinical research focuses on immunosuppression of Hepatitis B & C in liver, and kidney expanded criteria donors, and the immunosuppression of kidney transplantation.Renal transplantation, Liver transplantation, immunology, Hepatitis B & C, xenotransplantation

Keywords: 
Renal transplantation, Liver transplantation, immunology, Hepatitis B & C, xenotransplantation
Location: 
Royal Victoria Hospital
Publications:
Tchervenkov JI, Cantarovich M, Paraskevas S, Fernandez M, Baran D, Mangel R, Schiff J, Lipman M, Horton P, Metrakos P. Cadaveric Renal Transplantation and Expanded Criteria Donors: Should we reassess their use? Transplantation 2004; 78 :90.
Horton P, Deschenes M, Metrakos P, Barkun J, Cantarovich M, Tchervenkov JI. Incidence of Chronic Renal Failure in Liver Transplant Patients using Induction with Thymoglobulin and Delay in the Introduction of Calcineurin Inhibitors. Transplantation 2004; 78: 380-381.
Tchervenkov J, Tzimas G, Cantarovich M, Barkun J, Metrakos P. The impact of Tymoglobulin on renal function and calcineurin inhibitor initiation in recipients of orthotopic liver transplant: a retrospective analysis of 298 consecutive patients. Transplantation Proceedings 2004; 36: 1747-1752.