Indra Gupta, MD
Primary Axis:
Human Reproduction and Development
Email:
Email contact form Research Focus:
Congenital renal malformations are the most common cause of renal failure in children. My laboratory is interested in understanding the molecular basis of congenital kidney and urinary tract malformations using the mouse and cell lines as model systems.
Keywords:
Urinary tract development, tissue culture, embryology, dissection, kidney development, vesicoureteric reflux, kidney malformations, mouse genetics, claudins
Location:
Montreal Children's Hospital Publications:
Murawski IJ, Maina R, Malo D, Gros P, Guay-Woodford L, Fujiwara M, Morgan K, Gupta IR. The C3H/HeJ inbred mouse is a model of vesico-ureteric reflux and has a susceptibility locus on chromosome 12. Kidney International 2010 in press.
Gupta IR, Ryan AKR. Unlocking the code to tight junction function during embryogenesis and in disease. Clin Genet; 77: 314–325, 2010.
Murawski IJ, Myburgh D, Favor J, Gupta IR. The Pax21Neu mouse has vesico-ureteric reflux from a caudally shifted ureteric bud and a delay in lower urinary tract maturation, Am J Physiol Renal Physiol; 293(5): F1736-1745, 2007.
