Gloria S. Tannenbaum, PhD

The major objective of my research is to elucidate the brain mechanisms that regulate the rhythmic secretion of growth hormone (GH), a pituitary hormone that is essential for normal growth and metabolism. We have focused our efforts on two hypothalamic hormones, GH-releasing hormone and somatostatin, and, more recently, on the newly discovered stomach hormone, ghrelin, that exerts powerful effects on both GH secretion and appetite. The results of these studies may lead to the refinement of our clinical approaches to the diagnosis and treatment of GH deficiency, metabolic diseases and eating disorders.Growth hormone, somatostatin, growth hormone-releasing hormone, ghrelin, biological rhythms, energy balance, appetite, somatostatin receptor subtypes, hypothalamus