Feige Kaplan, PhD
Primary Axis:
Medical Genetics and Genomics
Secondary Axis:
Human Reproduction and Development
Email:
Email contact form Research Focus:
Research focuses on molecular determinants of early and late lung organogenesis; Investigations in novel steroid-responsive developmentally regulated genes important in lung branching and alveolarization. Also investigating the impact of steroid regulation on lung development in transgenic, knockout and conditional mouse models which are deficient in, or overexpress, the glucocorticoid receptor.Developmental biology/genetics, lung organogenesis, molecular organogenesis, neonatal lung disease, gene regulation, genetic screening
Keywords:
Developmental biology/genetics, lung organogenesis, molecular organogenesis, neonatal lung disease, gene regulation, genetic screening
Location:
Montreal Children's Hospital Publications:
Tao T, Lan J, Lukacs G, Hache R, Kaplan F. Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells. Am J Respir Cell Mol Biol 35(6): 668-680; 2006.
Nadeau K, Jankov RP, Tanswell AK, Sweezey NB, Kaplan F. Lgl1 is suppressed in oxygen toxicity models of bronchopulmonary dysplasia and normalizes during recovery in air. Pediatr Res 59: 389-395; 2006.
Tao T, Lan J, Presley J, Sweezey NB, Kaplan F. Nucleocytoplasmic shuttling of lgl2 is developmentally regulated in fetal lung. Am J Respir Cell Mol Biol 30: 350-359; 2004.
