Danuta Radzioch, PhD
Primary Axis:
Infection and Immunity
Email:
Email contact form Research Focus:
Research focuses on the effect of imidazoquinolines on the susceptibility to M. tuberculosis, M. bovis BCG and allergic asthma. The mechanism of macrophage activation for bactericidal activity are being studied, as is the role of inflammatory cytokines in cystic fibrosis and genetic factors regulating emphysema and asthma.Regulation of gene expression, macrophage activation, innate resistance, mycobacterial infection, posttranscriptional regulation, cystic fibrosis, asthma
Keywords:
Regulation of gene expression, macrophage activation, innate resistance, mycobacterial infection, posttranscriptional regulation, cystic fibrosis, asthma
Location:
Montreal General Hospital Publications:
Di Marco S, Moisan J, Boghdady ML, Skamene E, Radzioch D. Recombinant congenic strains of mice: a new tool for the genetic dissection of efficacy and toxicity of adjuvants. Vaccine 2003; 21: 832-835.
Guilbault C, Stotland P, Lachance C, Tam M, Keller A, Thompson-Snipes L, Cowley E, Hamilton TA, Eidelman DH, Stevenson MM, Radzioch D. Influence of gender and interleukin-10 deficiency on the inflammatory response during lung infection with Pseudomonas aeruginosa in mice. Immunology 2002; 107: 297-305.
Moisan J, Wojciechowski W, Guilbault C, Lachance C, Di Marco S, Skamene E, Matlashewski G, Radzioch D. Clearance of infection with Mycobacterium bovis BCG in mice is enhanced by treatment with S28463 (R-848), and its efficiency depends on expression of wild-type Nramp1 (resistance allele). Antimicrob Agents Chemotherapy 2001; 45: 3059-3064.
