Christina Haston, PhD
Primary Axis:
Respiratory Health
Email:
Email contact form Research Focus:
Research focuses on identifying the genes that predispose mice to developing the radiotherapy associated lung responses of pneumonitis and pulmonary fibrosis. The research combine the genomics approaches of linkage, congenic mouse studies, gene expression by microarray, DNA sequencing, and transgenic mouse evaluation.
Keywords:
Mouse genetics, linkage analysis, radiation-induced lung disease, radiotherapy, pulmonary fibrosis, genetic variation
Location:
Meakins-Christie Laboratories Publications:
Publications: Fox J, Gordon JR, Haston CK. Combined CXCR1/CXCR2 antagonism decreases radiation-induced alveolitis in the mouse. Radiat Res. 175(5):657-664; May 2011
Haston CK, Tsui LC. Loci of intestinal distress in cystic fibrosis knockout mice. Physiological Genomics;12:79-84; 2003
Haston CK, Wang M, Dejournett RE, Zhou X, Ni D, Gu X, King TM, Weil MM, Newman RA, Amos CI, Travis EL. Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice. Human Molecular Geneics; 11:1855-1863; 2002
Haston CK, McKerlie C, Newbigging S, Corey M, Rozmahel R, Tsui LC. Detection of modifier loci influencing the lung phenotype of cystic fibrosis knockout mice. Mammalian Genome; 13:605-613; 2002
