Bruno Gagnon, MD

Primary Axis: 
Health Outcomes
Secondary Axis: 
Cancer
Research Focus: 

Research focuses on the care of patients with cancer from basic sciences, patient reported outcomes and health services. Other interests include Health Care Services and the end of life, clinical trials for pain and symptoms management, pathophysiology and treatment of cognitive deficit and delirium, and the study of anorexia-cachexia and rehabilitation and nutrition interventions.

Keywords: 
Cancer, Palliative Care, Pain, Cachexia, Delirium, Rehabilitation, Health Care Services
Location: 
Montreal General Hospital
Publications:
Gagnon B, Abrahamowicz M, Xiao Y, MacDonald N, Kasymjanova G, Kreisman H, Small D. Flexible modeling improves assessment of prognostic value of C-reactive protein in advanced non-small cell lung cancer. Brit J Cancer; 102:1113-1122; 2010
Elie D, Gagnon P, Gagnon B, Giguère A. Utilisation des psychostimulants chez les patients en fin de vie atteints de délirium hypoactif et de troubles cognitifs: une revue de littérature, La Revue canadienne de psychiatrie, vol 55, no.6, juin 2010
Azoulay L, Dell’Aniello S, Gagnon B, Pollak M, Suissa S. Metformin and the incidence of prostate cancer in patients with type 2 diabetes. Cancer Epidemiology, Biomarkers & Prevention, Published OnlineFirst as 10.1158/1055-9965.EPI-10-0940; December 10, 2010
Gagnon P, Allard P, Gagnon B, Mérette C, Tardiff F. Delirium prevention in terminal cancer: Assessment of a multicomponent intervention. Psycho-Oncology. Published online in Wiley Online Library (wileyonlinelibrary.com). DOI: 10.1002/pon.1881; 2010
Rodriguez AM, Gagnon B, El lugar de muerte en pacientes con cáncer: ¿Que sabemos y que entendemos? Una revisión sistematica y crítica de la literatura. Medicina Paliativa. (2):111-119; March-April 18 2009
Wright J, Ung Y, Julian J, Pritchard K, Whelan T, Smith C, Szechtman B, Roa W, Mulroy L, Rudinskas L, Gagnon B, Okawara G, Levine M. Randomized, Double-Blind, Placebo-Controlled Trial of Erythropoietin in Non-Small-Cell Lung Cancer With Disease-Related Anemia. J Clin Oncol. 2007 Mar 20;25(9):1027-32. Epub 2007 Feb 20
Dudgeon DJ, Bruera E, Gagnon B, Watanabe SM, Allan SJ, Warr DG, MacDonald SM, Savage C, Tu D, Pater JL. A phase III randomized, double-blind, placebo-controlled study evaluating dextromethorphan plus slow-release morphine for chronic cancer pain relief in terminally ill patients. J Pain Symptom Manage. 2007 Apr;33(4):365-71.
Kosseim M, Mayo N, Scott S, Hanley J, Brophy J, Gagnon B, Pilote L. Ranking Hospitals According to Acute Myocardial Infarction Mortality. Should transfers be included? Med Care 44 (7): 664-670; 2006
Gagnon B, Laurin C, Mayo N, Hanley J.A., MacDonald N. Identification in Administrative Databases of Women dying of Breast Cancer. [Editorial: Earle CC., Looking back from death: The value of retrospective studies of end-of-life care. P.838-839.] Journal of Clinical Oncology 24 (6):865-862; 2006
Gagnon B, Greame L, Schreier G. Methylphenidate hydrochloride improves cognitive function in patients with advanced cancer and hypoactive delirium: a prospective clinical study, Journal of Psychiatry & Neuroscience, 30 (2): 100–107; 2005