Brian Ward, MD
Primary Axis:
Infection and Immunity
Email:
Email contact form Research Focus:
The laboratory has three major areas of interest in international health: 1) Vaccines from concept to community: projects include the development of novel vaccines for nasal administration (eg: measles, RSV, influenza), animal models for vaccine responses and to Phase I-IV clinical studies including investigations of vaccine-associated adverse events 2) Development of novel treatments and new diagnostic tests for neglected tropical diseases (e: Chagas Disease, Leishmania, dengue) and 3) Studies of micronutrient effects on both the immune responses and immunopathology associated with viral infections such as HIV in Africa, Paramyxoviridae (eg: measles, mumps, CDV, Sendai, RSV) and Myxoviridae (eg: influenza)
Keywords:
Infectious diseases, international health, vaccine immunology, vaccine adverse events, diagnostic parasitology, clinical parasitology
Publications:
Cyr SL, Angers I, Stoica-Popescu I, Lussier M, Qureshi S, Burt D, Ward BJ. Intranasal, Protollin-based RSV vaccination in mice: TLR4/MyD88 signaling is required both for protection and the control of pulmonary granulocyte recruitment following challenge. Vaccine 27:421-30; 2009.
Trottier C, Chabot S, Mann C, Miller W, Ward BJ. Retinoic acid inhibits measles virus replication in bystander cells through type-I interferon signaling pathways. FASEB J 2009 Sep;23(9):3203-12. Epub May 15
Ndao M, Spithill TW, Caffery R, Li HS, Duncan M, Ward BJ. Identification of Serum Biomarkers for the Diagnosis of Asymptomatic Parasitic Infection from Blood bank Using SELDI-ToF: Case of Chagas Disease. J Clin Microbiol 2010 (in press)
