Andrew Bateman, PhD
Primary Axis:
Cancer
Secondary Axis:
Endocrinology, Diabetes, Nutrition and Kidney Diseases
Email:
Email contact form Research Focus:
Progranulin (or PC-cell-derived growth factor/acrogranin/granulin-epithelin precursor) is a secreted protein that regulates cell proliferation, survival and invasion. It is involved in several cancers e.g. breast, kidney, glioma. We are interested in understanding the molecular basis of progranulin action in tumorigenisis and normal physiological processes such as wound repair.Growth factors, migration and invasion, cancer, wound repair
Keywords:
Growth factors, migration and invasion, cancer, wound repair
Location:
Royal Victoria Hospital Publications:
He Z, Bateman A. Progranulin (PC-cell-derived growth factor/acrogranin/granulin-epithelin precursor) in repair and tumorigenesis. Journal of Molecular Medicine 2003; 81: 600-612.
Daniel R, Daniels E, He Z, Bateman A. Progranulin (Acrogranin/PC-cell-derived growth factor/epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during development. Mechanisms of Development 2003; 227: 593-559.
He Z, Ong C, Halper J, Bateman A. Progranulin is a mediator of the wound response. Nature Medicine 2003; 9: 225-229.
