Amee Manges, PhD

Primary Axis: 
Infection and Immunity
Secondary Axis: 
Health Outcomes
Research Focus: 

Research focuses on investigating the epidemiology of bacterial infections and developing and facilitating the transfer of molecular biologic methods and technologies to epidemiologic studies and public health research and practice. The lab employs techniques in molecular epidemiology, bioinformatics, molecular biology, bacterial genetics and bacterial pathogenesis. Our current work centers on Escherichia coli that cause extraintestinal infections such as urinary tract infections (UTIs). Specific E. coli clonal groups may be responsible for outbreaks of community-acquired UTIs.molecular epidemiology, urinary tract infections, reproductive tract infections, community-acquired infections, Escherichia coli, bacterial pathogenesis, women’s health, public health

Keywords: 
molecular epidemiology, urinary tract infections, reproductive tract infections, community-acquired infections, Escherichia coli, bacterial pathogenesis, women’s health, public health
Location: 
Purvis Hall
Publications:
Manges AR, Natarajan P, Solberg OD, Dietrich PS, Riley LW. The changing prevalence of drug-resistant Escherichia coli clonal groups in a community: evidence for community outbreaks of urinary tract infections. Epidemiology and Infection 2005; (In press.)
Johnson JR, Manges AR, O’Bryan TT, Riley LW. A disseminated multidrug-resistant clonal group of uropathogenic Escherichia coli in pyelonephritis. Lancet 2002; 359: 2249-2251.
Manges AR, Johnson JR, Foxman B, O’Bryan TT, Fullerton KE, Riley LW. Widespread geographic distribution of a multidrug-resistant Escherichia coli clonal group causing community-acquired urinary tract infections. New England Journal of Medicine 2001; 345: 1007-1013.