Alain Ptito, PhD

Primary Axis: 
Neurosciences
Research Focus: 

Dr. Ptito's research program involves the investigation of the mechanisms involved in cerebral reorganization and plasticity in patient populations (hemispherectomy, callosotomy, Parkinson’s Disease, stroke and head injury) and his clinical work includes the neuropsychological assessment of these patients. His research is funded by CIHR, NSERC, FRSQ, CASM/NHL and the Heart and Stroke Foundation. For the past several years, he has been using functional magnetic resonance imaging (fMRI) to investigate motor recovery in stroke and the neural substrates of residual vision in the blind visual field following hemispherectomy. He has also demonstrated that this technique, along with Diffusion Tensor Imaging and evoked potentials, can be used to explore the neural mechanisms underlying acquired brain injury, particularly in athletes. With his research team, he has reported that there are abnormal activation patterns following acquired brain injury and that fMRI can serve as an objective method to assess the severity of the injury and subsequent recovery. Aside from his work with athletes, he is now using the results of his research for the head injury population at large, including adults and children.Psychology, neuropsychology, traumatic brain injury, hemispherectomy, callosotomy, Parkinson’s Disease, stroke, head injury, functional magnetic resonance imaging, fMRI.

Keywords: 
Psychology, neuropsychology, traumatic brain injury, hemispherectomy, callosotomy, Parkinson’s Disease, stroke, head injury, functional magnetic resonance imaging, fMRI.
Location: 
Montreal Neurological Institute and Hospital
Publications:
Chen JK, Johnston KM, Petrides M, Ptito A. Neural substrates of symptoms of depression following concussion in male athletes with persisting post-concussion symptoms. Archives of General Psychiatry. 2008; 65(1):81-89.
Ptito A, Chen JK, Johnston KM. Contributions of functional Magnetic Resonance Imaging (fMRI) to sport concussion evaluation. NeuroRehabilitation. 2007; 22(3):217-227.
Ptito, A., & Leh, S. (2007) Neural Substrates of Blindsight After hemispherectomy. Neuroscientist . 13; 506-518.